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S M Firth Selected Research

Insulin-Like Growth Factor Binding Protein 3

5/2013IGFBP-3 binds GRP78, stimulates autophagy and promotes the survival of breast cancer cells exposed to adverse microenvironments.
12/2000Insulin-like growth factor-binding protein-3 modulates expression of Bax and Bcl-2 and potentiates p53-independent radiation-induced apoptosis in human breast cancer cells.
12/2000Characterization of an amino-terminal fragment of insulin-like growth factor binding protein-3 and its effects in MCF-7 breast cancer cells.
8/2000Nuclear import of insulin-like growth factor-binding protein-3 and -5 is mediated by the importin beta subunit.

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S M Firth Research Topics

Disease

5Breast Neoplasms (Breast Cancer)
05/2013 - 08/2000
2Neoplasms (Cancer)
05/2013 - 05/2004
1Hypoxia (Hypoxemia)
05/2013
1Starvation
05/2013

Drug/Important Bio-Agent (IBA)

4Insulin-Like Growth Factor Binding Protein 3IBA
05/2013 - 08/2000
4Insulin-Like PeptidesIBA
05/2013 - 12/2000
3Proteins (Proteins, Gene)FDA Link
05/2013 - 12/2000
1Endoplasmic Reticulum Chaperone BiPIBA
05/2013
1Glucose (Dextrose)FDA LinkGeneric
05/2013
1Growth InhibitorsIBA
05/2013
1IGF Type 2 Receptor (Insulin-Like-Growth-Factor II Receptor)IBA
05/2004
1Apoptosis Regulatory ProteinsIBA
12/2000
1Transforming Growth Factor-beta Type II ReceptorIBA
12/2000
1Transforming Growth Factor beta (TGF-beta)IBA
12/2000
1Complementary DNA (cDNA)IBA
12/2000
1Insulin-Like Growth Factor Binding ProteinsIBA
12/2000
1EnzymesIBA
12/2000
1insulin-like growth factor binding protein-3 proteaseIBA
12/2000
1Insulin-Like Growth Factor I (IGF-1)IBA
12/2000
1DNA (Deoxyribonucleic Acid)IBA
12/2000
1Peptides (Polypeptides)IBA
12/2000
1Insulin-Like Growth Factor Binding Protein 5IBA
08/2000